PDE4D Antikörper (C-Term)

Produktnummer ABIN374635

Dieser Ziege Polyklonal Antikörper detektiert spezifisch PDE4D in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für PDE4D Antikörper (C-Term) (ABIN374635)

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Reaktivität: Human, Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PDE4D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-PDE4D Antikörper

Bindungsspezifität: C-Term

Sequenz: QPEACVIDDR SPDT

Spezifität: This antibody detects PDE4D at C-term and is expected to recognize all reported isoforms.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the C-Terminus of the protein sequence according to NP_001098101.1, NP_006194.2, NP_001159371.1. Genename: PDE4D

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/128000. Western Blot. : 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PDE4D

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Andere Bezeichnung: PDE4D

Hintergrund: Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3', 5'- monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE4 enzyme belongs to a family of cAMP-dependent PDEs that provide the major means of inactivating the key intracellular second messenger, cAMP. Four genes (4A, 4B, 4C, and 4D) encode around 20 distinct isoform members of the PDE4 family. Each isoform is characterized by a unique N-terminal region.Synonyms: 5'-cyclic phosphodiesterase 4D, DPDE3, EC=3.1.4.17, PDE43, PDE4D, cAMP-specific 3'

Gen-ID: 5144

NCBI Accession: NP_001098101

UniProt: Q08499

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling