PDE4D Antikörper (C-Term)

Produktnummer ABIN2855885

Produktdetails anti-PDE4D Antikörper

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE4D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Produktmerkmale: Rabbit Polyclonal antibody to PDE4D (phosphodiesterase 4D, cAMP-specific)
PDE4D antibody [C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PDE4D. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: A431 , HeLa

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.3 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PDE4D

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Andere Bezeichnung: phosphodiesterase 4D (PDE4D Produkte)

Synonyme: ACRDYS2 antikoerper, DPDE3 antikoerper, HSPDE4D antikoerper, PDE43 antikoerper, PDE4DN2 antikoerper, STRK1 antikoerper, CMYA2 antikoerper, MMGL antikoerper, 9630011N22Rik antikoerper, Dpde3 antikoerper, 4732458A06Rik antikoerper, 9430063L05Rik antikoerper, C87016 antikoerper, D130016K21Rik antikoerper, D3Bwg1078e antikoerper, Usmg4 antikoerper, mKIAA0454 antikoerper, si:dkey-190g11.2 antikoerper, phosphodiesterase 4D antikoerper, phosphodiesterase 4D interacting protein antikoerper, phosphodiesterase 4D, cAMP specific antikoerper, phosphodiesterase 4D, cAMP-specific antikoerper, phosphodiesterase 4D interacting protein (myomegalin) antikoerper, PDE4D antikoerper, PDE4DIP antikoerper, pde4d antikoerper, Pde4dip antikoerper, Pde4d antikoerper

Hintergrund: The PDE4D gene is complex and has at least 9 different isoforms that encode functional proteins. These proteins degrade the second messenger cAMP, which is a key signal transduction molecule in multiple cell types, including vascular cells (Dominiczak and McBride, 2003 [PubMed 14517535]).[supplied by OMIM]

Cellular Localization: Cytoplasm (By similarity) , Membrane (By similarity) , Cytoplasm , cytoskeleton (By similarity) , Centrosome (By similarity)

Molekulargewicht: 91 kDa

Gen-ID: 5144

UniProt: Q08499

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling