SH3GLB1 Antikörper (C-Term)

Produktnummer ABIN374106

Dieses Anti-SH3GLB1-Antikörper ist ein Ziege Polyklonal-Antikörper zur Detektion von SH3GLB1 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh) und Hund.

Kurzübersicht für SH3GLB1 Antikörper (C-Term) (ABIN374106)

Target: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser SH3GLB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SH3GLB1 Antikörper

Bindungsspezifität: C-Term

Sequenz: C-QKGKVPITYL ELLN

Spezifität: This antibody detects BIF1 / Endophilin-B1 at C-term.

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the C Terminus of the protein sequence according to NP_057093.1 Genename: SH3GLB1

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.3-1.0 μg/mL. Approx 38 kDa band observed in lysates of Human T cell lineJurkat and in Human Lung and Placenta (calculated MW of 40.8 kDa according toNP_057093.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Details zu SH3GLB1

Target: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Andere Bezeichnung: Endophilin-B1

Hintergrund: Bif is a member of the endophilin B protein family and may be an important component of the mitochondrial pathway for apoptosis, as a novel Bax/Bak activator. The loss of this proapoptotic molecule may contribute to tumorigenesis. Endophilins have been proposed to play roles in membrane trafficking reactions through interactions with endocytic protein via physical or chemical modifications of the membrane bilayer, particularly in presynaptic vesicle trafficking at nerve terminals. Bif (Endophilin B1), like endophilins A, binds to palmitoyl CoA and exhibits lysophosphatidic acid acyl transferase activity.Synonyms: BIF1, Bax-interacting factor 1, Bif-1, KIAA0491, SH3 domain-containing GRB2-like protein B1, SH3GLB1

Gen-ID: 51100

NCBI Accession: NP_057093

UniProt: Q9Y371

Pathways: Autophagie