SH3GLB1 Antikörper (AA 1-365)

Produktnummer ABIN7151644

Produktdetails anti-SH3GLB1 Antikörper

Target: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Bindungsspezifität: AA 1-365

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SH3GLB1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Endophilin-B1 protein (1-365AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SH3GLB1

Target: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Andere Bezeichnung: SH3GLB1 (SH3GLB1 Produkte)

Synonyme: im:5777505 antikoerper, wu:fa08f03 antikoerper, wu:fb13e12 antikoerper, MGC79086 antikoerper, sh3glb1 antikoerper, wu:fc55h11 antikoerper, wu:fj98d09 antikoerper, AA409932 antikoerper, AI314629 antikoerper, AU015566 antikoerper, Bif-1 antikoerper, mKIAA0491 antikoerper, PPP1R70 antikoerper, dJ612B15.2 antikoerper, SH3-domain GRB2-like endophilin B1b antikoerper, SH3 domain GRB2 like, endophilin B1 S homeolog antikoerper, SH3 domain GRB2 like, endophilin B1 antikoerper, SH3 domain containing GRB2 like, endophilin B1 antikoerper, SH3-domain GRB2-like endophilin B1a antikoerper, SH3-domain GRB2-like B1 (endophilin) antikoerper, SH3 domain -containing GRB2-like endophilin B1 antikoerper, SH3 domain containing GRB2 like endophilin B1 antikoerper, sh3glb1b antikoerper, sh3glb1.S antikoerper, sh3glb1 antikoerper, SH3GLB1 antikoerper, sh3glb1a antikoerper, Sh3glb1 antikoerper

Hintergrund:

Background: May be required for normal outer mitochondrial membrane dynamics (PubMed:15452144). Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion (PubMed:11604418). Involved in activation of caspase-dependent apoptosis by promoting BAX/BAK1 activation (PubMed:16227588). Isoform 1 acts proapoptotic in fibroblasts. Involved in caspase-independent apoptosis during nutrition starvation and involved in the regulation of autophagy. Activates lipid kinase activity of PIK3C3 during autophagy probably by associating with the PI3K complex II (PI3KC3-C2) (PubMed:17891140). Associated with PI3KC3-C2 during autophagy may regulate the trafficking of ATG9A from the Golgi complex to the peripheral cytoplasm for the formation of autophagosomes by inducing Golgi membrane tubulation and fragmentation (PubMed:21068542). Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123). Isoform 2 acts antiapoptotic in neuronal cells, involved in maintenance of mitochondrial morphology and promotes neuronal viability.

Aliases: Bax interacting factor 1 antibody, Bax-interacting factor 1 antibody, Bif 1 antibody, Bif antibody, Bif-1 antibody, CGI 61 antibody, dJ612B15.2 antibody, Endophilin B1 antibody, Endophilin-B1 antibody, PPP1R70 antibody, Protein phosphatase 1 regulatory subunit 70 antibody, SH3 containing protein SH3GLB1 antibody, SH3 domain GRB2 like endophilin B1 antibody, SH3 domain-containing GRB2-like protein B1 antibody, Sh3glb1 antibody, SH3p13 antibody, SHLB1_HUMAN antibody

UniProt: Q9Y371

Pathways: Autophagie