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RPS6KA3 Antikörper (C-Term)

RPS6KA3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Huhn WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN372713
  • Target Alle RPS6KA3 Antikörper anzeigen
    RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))
    Bindungsspezifität
    • 24
    • 23
    • 18
    • 17
    • 16
    • 15
    • 11
    • 10
    • 10
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 172
    • 113
    • 64
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Huhn
    Wirt
    • 173
    • 17
    • 1
    Kaninchen
    Klonalität
    • 173
    • 18
    Polyklonal
    Konjugat
    • 72
    • 11
    • 9
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    Dieser RPS6KA3 Antikörper ist unkonjugiert
    Applikation
    • 96
    • 68
    • 67
    • 53
    • 30
    • 25
    • 17
    • 17
    • 14
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    This antibody recognizes the ~90k RSK2 protein.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Bovine, Canine, Chicken, Mouse and Rat.
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity Chromatography.
    Immunogen
    Peptide corresponding to amino acid residues from the C-terminal region of rat RSK2, conjugated to keyhole limpet hemocyanin (KLH).
    Isotyp
    IgG
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  • Applikationshinweise
    Western blot: 1/1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody undiluted (in aliquots) at-20 °C.
  • Target
    RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))
    Andere Bezeichnung
    RPS6KA3 / RSK2 (RPS6KA3 Produkte)
    Hintergrund
    The p90 Ribosomal S6 kinases (RSK1-4) are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling (Sheffler et al., 2006).Synonyms: ISPK-1, ISPK1, MAPKAPK-1b, MAPKAPK1, RSK-2, Ribosomal S6 kinase 2, Ribosomal protein S6 kinase alpha-3, S6K-alpha-3, p90RSK3
    Gen-ID
    6197
    NCBI Accession
    NP_004577
    UniProt
    P51812
    Pathways
    MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
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