GRIA2 Antikörper (C-Term)

Produktnummer ABIN372655

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GRIA2 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Zebrafisch (Danio rerio) und Huhn.

Kurzübersicht für GRIA2 Antikörper (C-Term) (ABIN372655)

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio), Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GRIA2 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody is specific for the ~100k GluR2/3 protein.

Kreuzreaktivität (Details): Species reactivity (expected):Chicken, Human, Mouse and Zebrafish.
Species reactivity (tested):Rat.
Also reacts to: GLUR3

Aufreinigung: Affinity Chromatography.

Immunogen: Peptide corresponding to amino acid residues from the C-terminal region of rat GluR2/3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at-20 °C.

Details zu GRIA2

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Andere Bezeichnung: Glutamate Receptor 2 / GLUR2

Hintergrund: The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990,Hollmann and Heinemann, 1994). The GluR2 subunit is widely expressed throughout the nervous system where it is thought to play key roles in synaptic plasticity and learning and memory (Duprat et al., 2003,Seidenman et al., 2003,Chung et al., 2003,Yan et al., 2002).Synonyms: AMPA-selective glutamate receptor 2, AMPA2, GRIA2, GluR-B, GluR-K2, Glutamate receptor ionotropic

Gen-ID: 2891

NCBI Accession: NP_000817

UniProt: P42262

Pathways: PI3K-Akt Signalweg