MMP3 Antikörper

Produktnummer ABIN371657

Der Maus Monoklonal anti-MMP3 Antikörper wird verwendet zum Nachweis von MMP3 in Proben von Human. Er wurde validiert für IHC (p), IHC (fro) und EIA.

Kurzübersicht für MMP3 Antikörper (ABIN371657)

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MMP3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Klon: SB14d

Produktdetails anti-MMP3 Antikörper

Spezifität: This antibody is specific for Human MMP-3. Does not cross react to Human MMP-1, MMP-2 or MMP-9.

Produktmerkmale: Synonyms: Stromelysin-1, SL-1, Matrix metalloproteinase-3, Transin-1, MMP3, STMY1

Aufreinigung: Purified

Immunogen: Recombinant MMP-3.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA: 1/3,000-1/8,000. Immunohistochemistry (Frozen/Paraffin): < / = 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 100 mM Borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu MMP3

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Andere Bezeichnung: MMP-3

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP3 is an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. MMP3 is reported to be implicated in rheumatoid arthritis and some forms of cancer.Synonyms: MMP3, Matrix metalloproteinase-3, SL-1, STMY1, Stromelysin-1, Transin-1

Gen-ID: 4314

UniProt: P08254