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CD3 Antikörper

CD3 Reaktivität: Huhn FACS, IP, IHC (fro) Wirt: Maus Monoclonal CT-3 unconjugated

Produktnummer ABIN371328

Datenblatt (PDF)

Target Alle CD3 Antikörper anzeigen

CD3
Reaktivität
214

109

35

20

17

10

8

8

7

7

7

3

3

2

2
Huhn
Wirt
258

60

20

13

9

2
Maus
Passende Sekundärantikörper
Klonalität
350

6

1
Monoklonal
Konjugat
104

42

33

26

25

13

10

9

8

8

8

6

5

5

5

5

4

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD3 Antikörper ist unkonjugiert
Applikation
313

93

62

60

47

44

40

24

17

10

9

8

7

7

6

4

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktmerkmale

Synonyms: T3/Leu-4, T-cell surface glycoprotein CD3, T-cell surface antigen T3/Leu-4

Aufreinigung

Purified

Klon

CT-3

Isotyp

IgG1

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CD3 Reaktivität: Human, Non-Human Primate FACS, IP, IHC (fro), ICC, CyTOF Wirt: Maus Monoclonal UCHT1 unconjugated

anti-CD3 (CD3) antibody
CD3 Reaktivität: Human FACS, IP, CyTOF Wirt: Maus Monoclonal MEM-57 unconjugated

anti-CD3 (CD3) antibody
CD3 Reaktivität: Human FACS, IP, Func, CyTOF Wirt: Maus Monoclonal MEM-57 unconjugated

anti-CD3 (CD3) antibody
CD3 Reaktivität: Human, Non-Human Primate FACS, IP, IHC (fro), Func, CyTOF Wirt: Maus Monoclonal UCHT1 unconjugated

anti-CD3 (CD3) antibody (Biotin)
CD3 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal MEM-57 Biotin

anti-CD3 (CD3) antibody (Biotin)
CD3 Reaktivität: Human, Non-Human Primate FACS, IP, IHC (fro) Wirt: Maus Monoclonal UCHT1 Biotin

anti-CD3 (CD3) antibody (PerCP)
CD3 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal UCHT1 PerCP

anti-CD3 (CD3) antibody (PerCP)
CD3 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-57 PerCP

anti-CD3 (CD3) antibody (APC)
CD3 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-57 APC

Applikationshinweise

Flow Cytometry. Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections only). Immunoprecipitation. Immunosuppression of T cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

0.5 mg/mL

Buffer

100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit

12 months
Target

CD3

Andere Bezeichnung

CD3 (CD3 Produkte)

Hintergrund

T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits: CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82 % of normal peripheral blood lymphocytes, 65-85 % of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4

UniProt

Q98910

Pathways

T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway