CTLA4 Antikörper

Produktnummer ABIN371058

Dieser Anti-CTLA4 Antikörper ist ein Hamster Monoklonal Antikörper zur Detektion von CTLA4 in FACS, IP und Func. Geeignet für Maus.

Kurzübersicht für CTLA4 Antikörper (ABIN371058)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser CTLA4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Klon: 1B8

Produktdetails anti-CTLA4 Antikörper

Spezifität: This Monoclonal antibody is specific to CD152/CTLA-4.

Produktmerkmale: Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4

Aufreinigung: Purified

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry. (Ref.1,2)Immunoprecipitation. In vitro Functional Studies. (Ref.1,2)Enhancement of tumor immunity. (Ref.3)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Andere Bezeichnung: CD152 / CTLA4

Hintergrund: The lymphocyte surface antigen CD152, also known as CTLA-4, is related to the co-stimulatory molecule CD28, and both molecules share common B7 family counter-receptors. (Ref.1-4) However CD152 is thought to be a negative regulator of T cell activation (Ref.1-3) and may play a role in apoptotic control of T cells. CD152 exists as a 69 kDa homodimer (Ref.1), and is relatively conserved among Humans, Mice and Chickens. (Ref.2)Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4

Gen-ID: 100505288

UniProt: P09793

Pathways: Cancer Immune Checkpoints