CD72 Antikörper

Produktnummer ABIN371001

Der Maus Monoklonal anti-CD72 Antikörper (Klon 10-1-D-2) (ABIN371001) detektiert spezifisch CD72 in FACS und Func. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für CD72 Antikörper (ABIN371001)

Target: CD72 (CD72 Molecule (CD72))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD72 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Functional Studies (Func)

Klon: 10-1-D-2

Produktdetails anti-CD72 Antikörper

Spezifität: This antibody recognises CD72.1/Lyb-2.1 (Mr. 45 kDa). It blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. (Ref.1) However, 10-1.D.2 can itself trigger a positive signal by binding CD72. (Ref.1-5)

Produktmerkmale: Synonyms: Lyb-2, Ly-32, Ly32, B-Cell marker, B-cell differentiation antigen CD72, Lymphocyte antigen32

Aufreinigung: Purified

Immunogen: DBA/2 mouse spleen cells. (Ref. 1)

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Flow Cytometry. (Ref.1,2)Functional Assays: In vitro blocking and proliferation assays. (Ref.2,3)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD72

Target: CD72 (CD72 Molecule (CD72))

Andere Bezeichnung: CD72

Hintergrund: Murine CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells. (Ref.1,2)Synonyms: B-Cell marker, B-cell differentiation antigen CD72, Ly-32, Ly32, Lyb-2, Lymphocyte antigen 32

Gen-ID: 100504743

UniProt: P21855

Pathways: BCR Signaling