GRIA2 Antikörper (AA 878-882)
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- Target Alle GRIA2 Antikörper anzeigen
- GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
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Bindungsspezifität
- AA 878-882
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GRIA2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- The antibody detects endogenous level of total Glutamate receptor 2 (Precursor) protein.
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Peptide sequence around AA 878-882 (I-E-S-V-K) derived from Human Glutamate receptor 2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Isotyp
- IgG
- Top Product
- Discover our top product GRIA2 Primärantikörper
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- Applikationshinweise
- Western blotting: 1:500-1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Target
- GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
- Andere Bezeichnung
- Glutamate receptor 2 (Precursor) (GRIA2 Produkte)
- Hintergrund
- Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.
- Molekulargewicht
- 100 kDa
- NCBI Accession
- NP_000817
- UniProt
- P42262
- Pathways
- PI3K-Akt Signalweg
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