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EIF2A Antikörper (AA 49-53)

EIF2A Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN362970
  • Target Alle EIF2A Antikörper anzeigen
    EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))
    Bindungsspezifität
    • 17
    • 8
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 49-53
    Reaktivität
    • 83
    • 42
    • 41
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 69
    • 15
    Kaninchen
    Klonalität
    • 66
    • 18
    Polyklonal
    Konjugat
    • 45
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EIF2A Antikörper ist unkonjugiert
    Applikation
    • 66
    • 35
    • 34
    • 33
    • 14
    • 13
    • 13
    • 11
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Spezifität
    The antibody detects endogenous level of total eIF2a protein.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
    Immunogen
    Peptide sequence around AA 49-53 (E-L-S-R-R) derived from Human eIF2a. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Isotyp
    IgG
    Top Product
    Discover our top product EIF2A Primärantikörper
  • Applikationshinweise
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Immunofluorescence: 1:100-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Wu, Li, Lin, Wang, Li, Tie, Song, Guo, Yu, Li: "Salvianolic acid B protects human endothelial cells from oxidative stress damage: a possible protective role of glucose-regulated protein 78 induction." in: Cardiovascular research, Vol. 81, Issue 1, pp. 148-58, (2008) (PubMed).

  • Target
    EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))
    Andere Bezeichnung
    eIF2alpha (EIF2A Produkte)
    Synonyme
    ATEIF2-A2 antikoerper, EIF2-A2 antikoerper, eukaryotic translation initiation factor 2 alpha subunit antikoerper, EIF-2A antikoerper, MST089 antikoerper, MSTP004 antikoerper, MSTP089 antikoerper, D030048D22 antikoerper, D3Ertd194e antikoerper, im:7145971 antikoerper, zgc:110460 antikoerper, DDBDRAFT_0185936 antikoerper, DDBDRAFT_0234177 antikoerper, DDB_0185936 antikoerper, DDB_0234177 antikoerper, Eif2a antikoerper, eif2a antikoerper, eif2alpha antikoerper, EIF2A antikoerper, CG9946 antikoerper, Dmel\\CG9946 antikoerper, Eif2alpha antikoerper, IF2A_DROME antikoerper, M(1)14C antikoerper, M(1)19-153 antikoerper, M(1)8e3-10 antikoerper, deIF2alpha antikoerper, eIF-2 antikoerper, eIF-2 a antikoerper, eIF-2 alpha antikoerper, eIF2 alpha antikoerper, eIF2-alpha antikoerper, eIF2a antikoerper, eIF2alpha antikoerper, eiF-2alpha antikoerper, elF2alpha antikoerper, l(1)14Cf antikoerper, l(1)19-153 antikoerper, eukaryotic translation initiation factor 2 alpha subunit antikoerper, eukaryotic translation initiation factor 2A antikoerper, eukaryotic translation initiation factor 2A, 65kDa antikoerper, eukaryotic translation initiation factor 2A S homeolog antikoerper, eukaryotic translation initiation factor antikoerper, eukaryotic translation Initiation Factor 2alpha antikoerper, EIF2 ALPHA antikoerper, EIF2A antikoerper, Eif2a antikoerper, eif2a antikoerper, eIF2a antikoerper, eif2a.S antikoerper, eif2A antikoerper, eIF-2alpha antikoerper
    Hintergrund
    Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
    Molekulargewicht
    38 kDa
    NCBI Accession
    NP_004085
    UniProt
    P05198
    Pathways
    Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly
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