Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.

IGF1R Antikörper (AA 1163-1167)

Name: IGF1R Antikörper (AA 1163-1167)
SKU: ABIN362637
Price: 268.4 EUR
Availability: InStock

IGF1R Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated

(2 Referenzen)

Produktnummer ABIN362637

Datenblatt (PDF)

Target Alle IGF1R Antikörper anzeigen

IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
Bindungsspezifität
23

23

19

14

12

12

12

10

6

6

6

5

5

5

5

5

4

4

4

4

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1163-1167
Reaktivität
192

110

93

16

8

8

7

3

3

2

2

2

1

1

1
Human, Maus, Ratte
Wirt
172

33

2

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
174

35
Polyklonal
Konjugat
128

9

8

7

4

4

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

2
Dieser IGF1R Antikörper ist unkonjugiert
Applikation
131

72

64

61

33

26

18

13

13

11

5

4

4

3

2

1

1

1

1

1

1

1

1
Western Blotting (WB)

Spezifität

The antibody detects endogenous level of total IGF-1R protein.

Aufreinigung

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Peptide sequence around AA 1163-1167, 1164-1168 (T-D-Y-Y-R-K) derived from Human IGF-1R . Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotyp

IgG

Top Product

Discover our top product IGF1R Primärantikörper
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 251-350) antibody
IGF1R Reaktivität: Human, Maus, Ratte, Hund FACS Wirt: Kaninchen Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1346) antibody
IGF1R Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1165), (pTyr1166) antibody
IGF1R Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1161) antibody
IGF1R Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 51-77) antibody
IGF1R Reaktivität: Human WB, ELISA, IHC, FACS, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 1335-1366), (C-Term) antibody
IGF1R Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal RB01458 unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 51-77), (N-Term) antibody
IGF1R Reaktivität: Human WB, FACS, IF, IHC (p) Wirt: Kaninchen Polyclonal RB15292 unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (C-Term) antibody
IGF1R Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 660-760) antibody
IGF1R Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 763-955) antibody
IGF1R Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Western blotting: 1:500-1:1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Haghir, Rezaee, Nomani, Sankian, Kheradmand, Hami: "Sexual dimorphism in expression of insulin and insulin-like growth factor-I receptors in developing rat cerebellum." in: Cellular and molecular neurobiology, Vol. 33, Issue 3, pp. 369-77, (2013) (PubMed).

Han, Quirion, Zheng: "WITHDRAWN: Glutamate Attenuates IGF-1 Receptor Signaling via NR2B containing NMDA Receptors 3 and neuronal Nitric Oxide Synthase." in: Biochemical and biophysical research communications, (2011) (PubMed).
Target

IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Andere Bezeichnung

IGF-1R (IGF1R Produkte)

Hintergrund

This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.

Molekulargewicht

95 kDa

NCBI Accession

NP_000866

UniProt

P08069

Pathways

RTK Signalweg, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagie