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Cyclin E1 Antikörper (pThr395)

Der Kaninchen Polyklonal anti-Cyclin E1 Antikörper (ABIN362470) detektiert spezifisch Cyclin E1 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Produktnummer ABIN362470
378,40 €
Zzgl. Versandkosten 20,00 € und MwSt
Lieferung nach: Deutschland
Lieferung in 10 bis 14 Werktagen

Kurzübersicht für Cyclin E1 Antikörper (pThr395) (ABIN362470)

Target

Alle Cyclin E1 (CCNE1) Antikörper anzeigen
Cyclin E1 (CCNE1)

Reaktivität

  • 192
  • 36
  • 31
  • 4
  • 2
  • 2
  • 2
  • 1
Human

Wirt

  • 154
  • 39
Kaninchen

Klonalität

  • 109
  • 84
Polyklonal

Konjugat

  • 98
  • 11
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Cyclin E1 Antikörper ist unkonjugiert

Applikation

  • 147
  • 73
  • 62
  • 59
  • 44
  • 35
  • 28
  • 24
  • 22
  • 13
  • 11
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 32
    • 25
    • 16
    • 14
    • 11
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr395

    Spezifität

    The antibody detects endogenous level of Cyclin E1 only when phosphorylated at threonine 395.

    Aufreinigung

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

    Immunogen

    Peptide sequence around phosphorylation site of pThr395 (L-L-T (p) -P-P) derived from Human Cyclin E1 Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

    Isotyp

    IgG
  • Applikationshinweise

    Western blotting: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target

    Cyclin E1 (CCNE1)

    Andere Bezeichnung

    Cyclin E1

    Hintergrund

    The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition.

    Molekulargewicht

    48 kDa

    NCBI Accession

    NP_001229

    UniProt

    P24864

    Pathways

    Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases
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