Cyclin E1 Antikörper (pThr395)

Produktnummer ABIN362470

Produktdetails anti-Cyclin E1 Antikörper

Target: Cyclin E1 (CCNE1)

Bindungsspezifität: pThr395

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin E1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Spezifität: The antibody detects endogenous level of Cyclin E1 only when phosphorylated at threonine 395.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogen: Peptide sequence around phosphorylation site of pThr395 (L-L-T (p) -P-P) derived from Human Cyclin E1 Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blotting: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu Cyclin E1

Target: Cyclin E1 (CCNE1)

Andere Bezeichnung: Cyclin E1 (CCNE1 Produkte)

Synonyme: CCNE1 antikoerper, ccne antikoerper, cyclinE antikoerper, CCNE antikoerper, AW538188 antikoerper, CycE1 antikoerper, CYCLE antikoerper, Ccne antikoerper, cyce2 antikoerper, cycE3 antikoerper, cyce antikoerper, fa18e07 antikoerper, wu:fa18e07 antikoerper, cyclin E1 antikoerper, cyclin E1 L homeolog antikoerper, cyclin E1 S homeolog antikoerper, CCNE1 antikoerper, ccne1 antikoerper, Ccne1 antikoerper, ccne1.L antikoerper, ccne1.S antikoerper

Hintergrund: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition.

Molekulargewicht: 48 kDa

NCBI Accession: NP_001229

UniProt: P24864

Pathways: Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases