Aurora A Antikörper (pThr288)
Kurzübersicht für Aurora A Antikörper (pThr288) (ABIN362454)
Target
Alle Aurora A (AURKA) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pThr288
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Spezifität
- The antibody detects endogenous level of Aurora A only when phosphorylated at threonine 288.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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Immunogen
- Peptide sequence around phosphorylation site of pThr288 (R-T-T (p) -L-M) derived from Human Aurora A. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
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Isotyp
- IgG
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anti-Aurora Kinase A (AURKA) (AA 1-110) antibody
AURKA Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 5F8 unconjugated
anti-Aurora Kinase A (AURKA) (C-Term) antibodyAURKA Reaktivität: Human WB, IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Aurora Kinase A (AURKA) (AA 268-404) antibodyAURKA Reaktivität: Human WB, ELISA, IHC, ICC, FACS Wirt: Maus Monoclonal 2D8A4 unconjugated
anti-Aurora Kinase A (AURKA) (AA 364-392), (C-Term) antibodyAURKA Reaktivität: Human WB, IF, FACS Wirt: Kaninchen Polyclonal RB6834 unconjugated
anti-Aurora Kinase A (AURKA) antibodyAURKA Reaktivität: Human, Ratte, Affe WB, ELISA, ICC, FACS Wirt: Maus Monoclonal 1F8 unconjugated
anti-Aurora Kinase A (AURKA) (pThr288) antibodyAURKA Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Aurora Kinase A (AURKA) (AA 268-404) antibodyAURKA Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Maus Monoclonal 4H5A8 unconjugated
anti-Aurora Kinase A (AURKA) antibodyAURKA Reaktivität: Human, Ratte, Affe WB, ELISA, IHC Wirt: Maus Monoclonal 4G10 unconjugated
anti-Aurora Kinase A (AURKA) (AA 364-392) antibodyAURKA Reaktivität: Human WB, ELISA, IF, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Aurora Kinase A (AURKA) (AA 1-131) antibodyAURKA Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Immunohistochemistry: 1:50-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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Andere Bezeichnung
- Aurora A
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Hintergrund
- Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control. Phosphorylates numerous target proteins, including ARHGEF2, BRCA1, KIF2A, NDEL1, PARD3, PLK1 and BORA. Regulates KIF2A tubulin depolymerase activity By similarity. Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization.
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Molekulargewicht
- 48 kDa
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NCBI Accession
- NP_003591
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UniProt
- O14965
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Pathways
- Zellzyklus, Asymmetric Protein Localization
Target
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