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CDC25A Antikörper (pSer76)

CDC25A Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN362128
  • Target Alle CDC25A Antikörper anzeigen
    CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
    Bindungsspezifität
    • 34
    • 33
    • 21
    • 17
    • 15
    • 12
    • 9
    • 9
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer76
    Reaktivität
    • 235
    • 93
    • 77
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    Human, Maus, Ratte
    Wirt
    • 244
    • 7
    Kaninchen
    Klonalität
    • 245
    • 6
    Polyklonal
    Konjugat
    • 108
    • 21
    • 16
    • 15
    • 11
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser CDC25A Antikörper ist unkonjugiert
    Applikation
    • 193
    • 124
    • 69
    • 40
    • 40
    • 32
    • 21
    • 17
    • 15
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    The antibody detects endogenous level of cdc25A only when phosphorylated at serine 76.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    Immunogen
    Peptide sequence around phosphorylation site of pSer76 (M-G-S (p) -S-E) derived from Human cdc25A. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    Isotyp
    IgG
    Top Product
    Discover our top product CDC25A Primärantikörper
  • Applikationshinweise
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Piao, Lee, Xu, Gwak, Oh, Park, Ha: "CK1ε targets Cdc25A for ubiquitin-mediated proteolysis under normal conditions and in response to checkpoint activation." in: Cell cycle (Georgetown, Tex.), Vol. 10, Issue 3, pp. 531-7, (2011) (PubMed).

  • Target
    CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
    Andere Bezeichnung
    cdc25A (CDC25A Produkte)
    Synonyme
    cdc25a2 antikoerper, cdc25A antikoerper, sb:cb317 antikoerper, CDC25A2 antikoerper, D9Ertd393e antikoerper, cell division cycle 25A antikoerper, cell division cycle 25B antikoerper, cell division cycle 25A S homeolog antikoerper, CDC25A antikoerper, cdc25a antikoerper, cdc25b antikoerper, Cdc25a antikoerper, cdc25a.S antikoerper
    Hintergrund
    Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDC2 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.
    Molekulargewicht
    70 kDa
    NCBI Accession
    NP_001780
    UniProt
    P30304
    Pathways
    Zellzyklus, Mitotic G1-G1/S Phases, M Phase
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