beta Catenin Antikörper (pSer45)
Kurzübersicht für beta Catenin Antikörper (pSer45) (ABIN362090)
Target
Alle beta Catenin (CATNB) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer45
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Spezifität
- The antibody detects endogenous level of b-Catenin only when phosphorylated at threonine 41/serine 45.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
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Immunogen
- Peptide sequence around phosphorylation site of pThr 41, pSer45 (A-T-T (p) -T-A-P-S (p) -L-S) derived from Human b-Catenin. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
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Isotyp
- IgG
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Applikationshinweise
- Western blotting: 1:500-1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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Andere Bezeichnung
- beta-Catenin
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Hintergrund
- Involved in the regulation of cell adhesion and in signal transduction through the Wnt pathway.
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Molekulargewicht
- 92 kDa
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NCBI Accession
- NP_001091
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UniProt
- P35222
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Pathways
- Peptide Hormone Metabolism
Target
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