RPS6KA2 Antikörper (C-Term)
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- Target Alle RPS6KA2 Antikörper anzeigen
- RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))
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Bindungsspezifität
- C-Term
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RPS6KA2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- Specific for the ~90k RSK2 protein.
- Kreuzreaktivität
- Human
- Homologie
- bovine, canine, chicken, mouse, rat
- Aufreinigung
- Antigen Affinity Purified from Pooled Serum
- Immunogen
- Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH
- Top Product
- Discover our top product RPS6KA2 Primärantikörper
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- Applikationshinweise
- Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
- Lagerung
- -20 °C
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Phosphodiesterase 11A (PDE11A), Enriched in Ventral Hippocampus Neurons, is Required for Consolidation of Social but not Nonsocial Memories in Mice." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 41, Issue 12, pp. 2920-2931, (2017) (PubMed).
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Phosphodiesterase 11A (PDE11A), Enriched in Ventral Hippocampus Neurons, is Required for Consolidation of Social but not Nonsocial Memories in Mice." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 41, Issue 12, pp. 2920-2931, (2017) (PubMed).
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- Target
- RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))
- Andere Bezeichnung
- RPS6KA2 (RPS6KA2 Produkte)
- Hintergrund
- The p90 ribosomal S6 kinases (RSK)1–4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin–Lowry syndrome, which is characterized by mental retardation and growth deficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling (Sheffler et al., 2006). Anti-Ribosomal S6 Kinase Western blot of rat hippocampal lysate showing specific immunolabeling of the ~90k RSK2 protein.
- Molekulargewicht
- '90 kDa
- Gen-ID
- 20112
- UniProt
- Q9WUT3
- Pathways
- MAPK Signalweg, Neurotrophin Signalübertragung, Regulation of Systemic Arterial Blood Pressure by Hormones, Activation of Innate immune Response, Toll-Like Receptors Cascades
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