MAPT Antikörper (pSer416)

Produktnummer ABIN361456

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MAPT in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Ratte.Es wurde in 1 Publikation zitiert.

Kurzübersicht für MAPT Antikörper (pSer416) (ABIN361456)

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-MAPT Antikörper

Bindungsspezifität: pSer416

Spezifität: Specific for ~59, 65, 68 kDa tau protein phosphorylated at Ser416. Immunolabeling is blocked by preadsorption with the phosphopeptide used as antigen, but not by the corresponding non-phosphopeptide.

Kreuzreaktivität: Human, Maus, Ratte

Homologie: bovine, canine, human, non-human primate

Produktmerkmale: Our Tau (Ser416) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects Tau (Ser416) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC.

Aufreinigung: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser416 of rat tau, conjugated to keyhole limpet hemocyanin (KLH).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Dilution Range: WB Brain: 1:1000

Dilution Range: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Haltbarkeit: 12 months

Referenzen für anti-MAPT Antikörper (ABIN361456)

Wang, Hall, Lee, Kamgar-Parsi, Bi, Baudry: "The tyrosine phosphatase PTPN13/FAP-1 links calpain-2, TBI and tau tyrosine phosphorylation." in: Scientific reports, Vol. 7, Issue 1, pp. 11771, (2019) (PubMed).

Details zu MAPT

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Andere Bezeichnung: MAPT

Hintergrund:

Synonyms: AI413597 antibody, AW045860 antibody, DDPAC antibody, FLJ31424 antibody, FTDP 17 antibody, G protein beta1/gamma2 subunit interacting factor 1 antibody, MAPT antibody, MAPTL antibody, MGC134287 antibody, MGC138549 antibody, MGC156663 antibody, Microtubule associated protein tau antibody, Microtubule associated protein tau isoform 4 antibody, Microtubule-associated protein tau antibody, MSTD antibody, Mtapt antibody, MTBT1 antibody, MTBT2 antibody, Neurofibrillary tangle protein antibody, Paired helical filament tau antibody, Paired helical filament-tau antibody, PHF tau antibody, PHF-tau antibody, PPND antibody, PPP1R103 antibody, Protein phosphatase 1 regulatory subunit 103 antibody, pTau antibody, RNPTAU antibody, TAU antibody, TAU_HUMAN antibody, Tauopathy and respiratory failure included antibody

Description Logic: Our Tau (Ser416) rabbit polyclonal phosphospecific primary antibody is produced . It detects Tau (Ser416) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC.

Gene Name Alternatives: MAPT

Molekulargewicht: 59 kDa/65 kDa/68 kDa

Gen-ID: 69329

UniProt: P19332

Pathways: MAPK Signalweg, Microtubule Dynamics, M Phase, Regulation of Cell Size