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GRIA2 Antikörper

GRIA2 Reaktivität: Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN361453
  • Target Alle GRIA2 Antikörper anzeigen
    GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
    Reaktivität
    • 88
    • 66
    • 59
    • 11
    • 9
    • 9
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 86
    • 14
    Kaninchen
    Klonalität
    • 75
    • 25
    Polyklonal
    Konjugat
    • 55
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser GRIA2 Antikörper ist unkonjugiert
    Applikation
    • 83
    • 27
    • 27
    • 27
    • 25
    • 16
    • 15
    • 8
    • 8
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    Specific for the ~100k GluR2 protein.
    Kreuzreaktivität
    Ratte (Rattus)
    Homologie
    chicken, human, mouse, non-human primate, Zebrafish
    Aufreinigung
    Antigen Affinity Purified from Pooled Serum
    Immunogen
    Synthetic peptide corresponding to amino acid residues specific to GluR2 conjugated to KLH
    Top Product
    Discover our top product GRIA2 Primärantikörper
  • Applikationshinweise
    Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
    Lagerung
    -20 °C
  • Target
    GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
    Andere Bezeichnung
    GRIA2 (GRIA2 Produkte)
    Hintergrund
    The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by (-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990,Hollmann and Heinemann, 1994). The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD (Chung et al., 2003) Anti-GluR2 Western blot of a rat hippocampal (Hipp) lysate showing the specific immunolabeling of the ~100k GluR2 protein.
    Molekulargewicht
    '100 kDa
    Gen-ID
    29627
    UniProt
    P19491
    Pathways
    PI3K-Akt Signalweg
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