GRIA2 Antikörper
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- Target Alle GRIA2 Antikörper anzeigen
- GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GRIA2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- Specific for the ~100k GluR2 protein.
- Kreuzreaktivität
- Ratte (Rattus)
- Homologie
- chicken, human, mouse, non-human primate, Zebrafish
- Aufreinigung
- Antigen Affinity Purified from Pooled Serum
- Immunogen
- Synthetic peptide corresponding to amino acid residues specific to GluR2 conjugated to KLH
- Top Product
- Discover our top product GRIA2 Primärantikörper
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- Applikationshinweise
- Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
- Lagerung
- -20 °C
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- Target
- GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
- Andere Bezeichnung
- GRIA2 (GRIA2 Produkte)
- Hintergrund
- The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by (-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990,Hollmann and Heinemann, 1994). The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD (Chung et al., 2003) Anti-GluR2 Western blot of a rat hippocampal (Hipp) lysate showing the specific immunolabeling of the ~100k GluR2 protein.
- Molekulargewicht
- '100 kDa
- Gen-ID
- 29627
- UniProt
- P19491
- Pathways
- PI3K-Akt Signalweg
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