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IL15RA Antikörper (Extracellular Domain)

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch IL15RA in WB. Er zeigt eine Reaktivität gegenüber Maus.
Produktnummer ABIN360913

Kurzübersicht für IL15RA Antikörper (Extracellular Domain) (ABIN360913)

Target

Alle IL15RA Antikörper anzeigen
IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Reaktivität

  • 53
  • 26
  • 13
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Maus

Wirt

  • 45
  • 8
  • 2
  • 1
Ratte

Klonalität

  • 44
  • 12
Monoklonal

Konjugat

  • 22
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser IL15RA Antikörper ist unkonjugiert

Applikation

  • 44
  • 23
  • 13
  • 13
  • 9
  • 4
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

Klon

6C38
  • Bindungsspezifität

    • 15
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain

    Spezifität

    This antibody detects IL-15Ralpha. No cross activity to other IGFBPs.

    Aufreinigung

    Protein A/G affinity chromatography

    Immunogen

    Recombinant protein of IL-15Ralpha extracellular domain.

    Isotyp

    IgG2
  • Applikationshinweise

    Western Blot: 1/500 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Rekonstitution

    Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

    Andere Bezeichnung

    IL15RA

    Hintergrund

    IL15RA is a cytokine receptor that specifically binds IL15 with high affinity. It shares two subunits with the receptor of IL2, the IL2R beta and IL2R gamma chains. This forms the basis of many overlapping biological activities of IL15 and IL2. The IL2 receptor requires an additional IL2-specific alpha subunit for high affinity IL2 binding. This protein is structurally related to IL2R alpha, but is capable of binding IL15 with high affinity independent of other subunits, which suggests the distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. There are nine different isoforms.Synonyms: IL-15R-alpha, IL-15RA, Interleukin-15 receptor subunit alpha

    Gen-ID

    16169

    NCBI Accession

    NP_032384

    UniProt

    Q60819

    Pathways

    JAK-STAT Signalweg
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