Dual Specificity Phosphatase 3 (DUSP3) (N-Term) Antikörper

Produktnummer ABIN360840

Der Kaninchen Polyklonal anti-Dual Specificity Phosphatase 3 Antikörper (ABIN360840) detektiert spezifisch Dual Specificity Phosphatase 3 in WB, IHC (p) und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Dual Specificity Phosphatase 3 (DUSP3) (N-Term) Antikörper (ABIN360840)

Target: Dual Specificity Phosphatase 3 (DUSP3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to DUSP3.

Aufreinigung: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human DUSP3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western Blot: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Antigendetails

Target: Dual Specificity Phosphatase 3 (DUSP3)

Andere Bezeichnung: DUSP3

Hintergrund: DUSP3 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.Synonyms: Dual specificity protein phosphatase 3, Dual specificity protein phosphatase VHR, VHR, Vaccinia H1-related phosphatase

Gen-ID: 1845, 9606

UniProt: P51452

Pathways: Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades