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Dual Specificity Phosphatase 3 (DUSP3) (AA 157-185), (C-Term) Antikörper

DUSP3 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB5730 unconjugated
Produktnummer ABIN392859
  • Target Alle Dual Specificity Phosphatase 3 (DUSP3) Antikörper anzeigen
    Dual Specificity Phosphatase 3 (DUSP3)
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 157-185, C-Term
    Reaktivität
    • 40
    • 21
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 50
    • 8
    Kaninchen
    Klonalität
    • 50
    • 8
    Polyklonal
    Konjugat
    • 26
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Unkonjugiert
    Applikation
    • 40
    • 23
    • 14
    • 13
    • 13
    • 11
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This DUSP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-185 amino acids from the C-terminal region of human DUSP3.
    Klon
    RB5730
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product DUSP3 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    Dual Specificity Phosphatase 3 (DUSP3)
    Andere Bezeichnung
    DUSP3 (DUSP3 Produkte)
    Synonyme
    dusp3 antikoerper, si:bz18k17.3 antikoerper, si:rp71-18k17.3 antikoerper, VHR antikoerper, RGD1560049 antikoerper, 2210015O03Rik antikoerper, 5031436O03Rik antikoerper, T-DSP11 antikoerper, dual specificity phosphatase 3 antikoerper, dual specificity phosphatase 3b antikoerper, dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) antikoerper, DUSP3 antikoerper, dusp3b antikoerper, Dusp3 antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund
    DUSP3 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. The gene for this protein maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer.
    Molekulargewicht
    20478
    Gen-ID
    1845
    NCBI Accession
    NP_004081
    UniProt
    P51452
    Pathways
    Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
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