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EGFR Antikörper (Ser1070)

Dieses Anti-EGFR-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von EGFR in WB, IHC (p) und EIA. Geeignet für Human und Maus.
Produktnummer ABIN359838

Kurzübersicht für EGFR Antikörper (Ser1070) (ABIN359838)

Target

Alle EGFR Antikörper anzeigen
EGFR (Epidermal Growth Factor Receptor (EGFR))

Reaktivität

  • 853
  • 301
  • 289
  • 25
  • 25
  • 24
  • 20
  • 14
  • 8
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 613
  • 241
  • 14
  • 13
  • 5
  • 4
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 545
  • 343
  • 2
Polyklonal

Konjugat

  • 467
  • 66
  • 28
  • 21
  • 18
  • 18
  • 18
  • 17
  • 16
  • 16
  • 16
  • 13
  • 13
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 9
  • 9
  • 9
  • 9
  • 9
  • 8
  • 8
  • 2
  • 1
  • 1
  • 1
Dieser EGFR Antikörper ist unkonjugiert

Applikation

  • 613
  • 265
  • 211
  • 169
  • 148
  • 129
  • 102
  • 92
  • 83
  • 82
  • 37
  • 33
  • 33
  • 27
  • 19
  • 11
  • 8
  • 6
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 42
    • 39
    • 31
    • 31
    • 30
    • 29
    • 27
    • 27
    • 26
    • 22
    • 22
    • 18
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 15
    • 13
    • 12
    • 12
    • 11
    • 10
    • 10
    • 9
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Ser1070

    Spezifität

    This antibody reacts to EGFR.

    Aufreinigung

    Protein A column, followed by peptide affinity purification

    Immunogen

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S1070 of human EGFR.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target

    EGFR (Epidermal Growth Factor Receptor (EGFR))

    Andere Bezeichnung

    EGFR / ERBB1

    Hintergrund

    The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.Synonyms: EGF Receptor, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, c-ErbB-1, erbB-1

    Gen-ID

    1956, 9606

    UniProt

    P00533

    Pathways

    NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
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