EPH Receptor A3 Antikörper (C-Term)

Produktnummer ABIN359793

Dieses Anti-EPH Receptor A3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von EPH Receptor A3 in WB, IHC (p) und EIA. Geeignet für Human und Hamster.

Kurzübersicht für EPH Receptor A3 Antikörper (C-Term) (ABIN359793)

Target: EPH Receptor A3 (EPHA3)

Reaktivität: Human, Hamster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-EPH Receptor A3 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to EphA3.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human EphA3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu EPH Receptor A3

Target: EPH Receptor A3 (EPHA3)

Andere Bezeichnung: EPHA3

Hintergrund: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: EK4, EPH-like kinase 4, ETK, ETK1, Eph-like tyrosine kinase 1, Ephrin type-A receptor 3, HEK, Human embryo kinase, TYRO4, Tyrosine-protein kinase TYRO4, Tyrosine-protein kinase receptor ETK1, hEK4

Gen-ID: 2042, 9606

UniProt: P29320

Pathways: RTK Signalweg, Regulation of Cell Size