PLK2 Antikörper (C-Term)

Produktnummer ABIN359469

Dieses Anti-PLK2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PLK2 in WB, IHC (p) und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für PLK2 Antikörper (C-Term) (ABIN359469)

Target: PLK2 (Polo-Like Kinase 2 (PLK2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-PLK2 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects PLK2 (SNK) at C-term.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SNK.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA 1: 1,000. Western blot 1: 100 - 1-500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu PLK2

Target: PLK2 (Polo-Like Kinase 2 (PLK2))

Andere Bezeichnung: PLK2 / SNK

Hintergrund: Plks (polo-like kinases) encode serine/threonine kinases that are closelyrelated to polo and CDC5, genes that are required for passage through mitosisin Drosophila and Saccharomyces, respectively. Polo-like kinases, whichinclude Plk, Snk (for serum-inducible kinase, also designated Plk2) and Fnk(for FGF-inducible kinase, also designated Plk3 or PRK), play a role in cellproliferation. Plk protein accumulates in the cell during S and G2 phases ofthe cell cycle, and both protein content and catalytic activity peak at theonset of mitosis, followed by a rapid reduction after mitosis. Snk and Fnk areimmediate-early response genes that are first expressed during G1 phase. SNK may play a role in the division of at least some cell types, such as fibroblasts, and could function in embryogenesis, wound healing or neoplasia SNK mRNA is rapidly induced in human lung fibroblasts upon reintroduction of serum following 36 hours of serum deprivation.Synonyms: PLK-2, Polo-like kinase 2, Serine/threonine-protein kinase PLK2, Serine/threonine-protein kinase SNK, Serum-inducible kinase

Molekulargewicht: 78236 Da

Gen-ID: 10769, 9606

UniProt: Q9NYY3