PINK1 Antikörper (N-Term)

Produktnummer ABIN358994

Der Kaninchen Polyklonal anti-PINK1 Antikörper wird verwendet zum Nachweis von PINK1 in Proben von Human. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für PINK1 Antikörper (N-Term) (ABIN358994)

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PINK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-PINK1 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to PINK1 (PARK6).

Aufreinigung: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide in the N-terminal region of human Park6 (PINK1).

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu PINK1

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Andere Bezeichnung: PINK1

Hintergrund: Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.Synonyms: BRPK, PARK6, PINK-1, PTEN-induced putative kinase protein 1, Parkinson disease (autosomal recessive) 6, Serine/threonine-protein kinase PINK1, mitochondrial

Gen-ID: 65018, 9606

UniProt: Q9BXM7

Pathways: Autophagie