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TLR6 Antikörper (N-Term)

TLR6 Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN357054
  • Target Alle TLR6 Antikörper anzeigen
    TLR6 (Toll-Like Receptor 6 (TLR6))
    Bindungsspezifität
    • 18
    • 8
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 68
    • 25
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 57
    • 19
    • 1
    Kaninchen
    Klonalität
    • 57
    • 20
    Polyklonal
    Konjugat
    • 38
    • 10
    • 8
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TLR6 Antikörper ist unkonjugiert
    Applikation
    • 49
    • 45
    • 36
    • 28
    • 10
    • 9
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects TLR6 at N-term.
    Aufreinigung
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of mouse TLR6.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product TLR6 Primärantikörper
  • Applikationshinweise
    ELISA 1: 1,000. Immunohistochemistry 1: 50 - 1: 100. Western blot 1: 200 - 1: 500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target
    TLR6 (Toll-Like Receptor 6 (TLR6))
    Andere Bezeichnung
    CD286 / TLR6 (TLR6 Produkte)
    Synonyme
    TLR1 antikoerper, TLR16 antikoerper, CD286 antikoerper, TLR-6 antikoerper, toll-like receptor 1 family member A antikoerper, toll like receptor 6 antikoerper, toll-like receptor 6 antikoerper, TLR1A antikoerper, TLR6 antikoerper, Tlr6 antikoerper
    Hintergrund
    TLR6, a Type I membrane protein that belongs to the Toll-like rceptor family, participates in the innate immune response to Gram-positive bacteria and fungi. It acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. The protein recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. It binds to TLR2 via their respective extracellular domains, and to MyD88 via their respective TIR domains. TLR6 is detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells.Synonyms: Toll-like receptor 6
    Gen-ID
    21899, 10090
    UniProt
    Q9EPW9
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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