PINK1 Antikörper
Kurzübersicht für PINK1 Antikörper (ABIN356392)
Target
Alle PINK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This antibody is specific to PINK1.
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Produktmerkmale
- Synonyms: PTEN-induced putative kinase protein 1, PARK6, BRPK, PINK-1, Serine/threonine-proteinkinase PINK1, mitochondrial, Parkinson disease (autosomal recessive) 6
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Aufreinigung
- Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Immunogen
- Recombinant PINK1 protein was used to produced this monoclonal antibody.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/1,000. Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures. -
Haltbarkeit
- 12 months
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- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
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Andere Bezeichnung
- PINK1
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Hintergrund
- Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.Synonyms: BRPK, PARK6, PINK-1, PTEN-induced putative kinase protein 1, Parkinson disease (autosomal recessive) 6, Serine/threonine-protein kinase PINK1, mitochondrial
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Gen-ID
- 65018
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UniProt
- Q9BXM7
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Pathways
- Autophagie
Target
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