Der Maus Monoklonal anti-PINK1 Antikörper (Klon 38CT18-7) (ABIN356391) detektiert spezifisch PINK1 in WB und IHC (p).
Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.
ELISA: 1/1,000. Western blotting: 1/500-1/2000. Immunohistochemistry: 1/100-1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Haltbarkeit
12 months
Target
PINK1
(PTEN Induced Putative Kinase 1 (PINK1))
Andere Bezeichnung
PINK1
Hintergrund
Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.Synonyms: BRPK, PARK6, PINK-1, PTEN-induced putative kinase protein 1, Parkinson disease (autosomal recessive) 6, Serine/threonine-protein kinase PINK1, mitochondrial