Nanog Antikörper
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- Target Alle Nanog (NANOG) Antikörper anzeigen
- Nanog (NANOG) (Nanog Homeobox (NANOG))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Nanog Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody is specific to Human NANOG.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
- Produktmerkmale
- Synonyms: Homeobox protein NANOG
- Aufreinigung
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Immunogen
- This antibody is generated from mouse immunized with human recombinant NANOGprotein.
- Klon
- 60CT70-5-12
- Isotyp
- IgG1
- Top Product
- Discover our top product NANOG Primärantikörper
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- Applikationshinweise
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ELISA: 1/1,000. Western blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS, 0.09 % (W/V) Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Haltbarkeit
- 12 months
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- Target
- Nanog (NANOG) (Nanog Homeobox (NANOG))
- Andere Bezeichnung
- NANOG (NANOG Produkte)
- Synonyme
- 2410002E02Rik antikoerper, ENK antikoerper, ecat4 antikoerper, NANOG antikoerper, hacp antikoerper, wu:fd19e04 antikoerper, wu:fd20a07 antikoerper, zgc:193933 antikoerper, Nanog homeobox antikoerper, nanog homeobox antikoerper, Nanog antikoerper, NANOG antikoerper, nanog antikoerper
- Hintergrund
- NANOG is a transcription regulator involved in inner cell mass and embryonic stem (ES) cell proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation.Synonyms: Homeobox protein NANOG
- Molekulargewicht
- 34620 Da
- Gen-ID
- 79923
- UniProt
- Q9H9S0
- Pathways
- Stem Cell Maintenance
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