LIN28A Antikörper

Produktnummer ABIN356385

Dieses Anti-LIN28A-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von LIN28A in WB, IHC (p) und EIA. Geeignet für Human.

Kurzübersicht für LIN28A Antikörper (ABIN356385)

Target: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LIN28A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Klon: 55CT58-12-1

Produktdetails anti-LIN28A Antikörper

Spezifität: This antibody is specific to LIN28A.

Produktmerkmale: Synonyms: LIN-28, LIN28A, CSDD1, ZCCHC1, Lin-28 homolog A

Aufreinigung: Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: LIN28A recombinant protein is used to produce this monoclonal antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000. Western blotting: 1/200-1/2000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu LIN28A

Target: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Andere Bezeichnung: LIN28

Hintergrund: LIN28A acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. It is essential for skeletal muscle differentiation through the translational up-regulation of IGF2 expression.Synonyms: CSDD1, LIN-28, LIN28A, Lin-28 homolog A, ZCCHC1

Gen-ID: 79727

UniProt: Q9H9Z2

Pathways: Stem Cell Maintenance