Der Kaninchen Polyklonal anti-ACTH Antikörper wird verwendet zum Nachweis von ACTH in Proben von Human und Ratte. Er wurde validiert für IF, WB und ICC.
ACTH
Reaktivität: Human, Ratte
IF (p), IF (cc)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 750
Applikationshinweise
Optimal working dilutions should be determined experimentally by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Lagerung
RT
Target
ACTH
(Adrenocorticotropic hormone (ACTH))
Andere Bezeichnung
ACTH
Substanzklasse
Hormone
Hintergrund
Adrenocorticotropin (ACTH) occurs in cells of the anterior pituitary and in neurons in brain. It regulates the corticosteroid production in the adrenal cortex. Beta endorphin and Met enkephalin are endogenous opiates. MSH (melanocyte stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes. ACTH can alter pain sensitivity. The effect of corticosteroids, like ACTH on the sensitivity to pain is an indirect one by virtue of their negative feed-back action on the hypothalamic-pituitary system.