Caveolin-1 Antikörper (AA 30-80)

Produktnummer ABIN350196

Dieses Anti-Caveolin-1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Caveolin-1 in WB und IHC. Geeignet für Human.

Kurzübersicht für Caveolin-1 Antikörper (AA 30-80) (ABIN350196)

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caveolin-1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Caveolin-1 Antikörper

Bindungsspezifität: AA 30-80

Verwendungszweck: Rabbit antibody to CAV1 (30-80)

Spezifität: Specific for Caveolin-1.

Kreuzreaktivität: Human, Maus, Ratte

Kreuzreaktivität (Details): Other species not yet tested.

Aufreinigung: IgG

Immunogen: A synthetic peptide from AA 30-80 of human Caveolin 1 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in many other species including rat mouse.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu Caveolin-1

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Andere Bezeichnung: CAV1

Hintergrund: FUNCTION: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. SUBCELLULAR LOCATION: Golgi apparatus membrane, Single-pass membrane protein. Cell membrane, Single-pass membrane protein. Note: Potential hairpin-like structure in the membrane. Membrane protein of protein of caveolae. TISSUE SPECIFICITY: In muscle and lung less so in liver brain and kidney.

UniProt: Q03135

Pathways: Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals