Caldesmon Antikörper

Produktnummer ABIN347045

Der Kaninchen Polyklonal anti-Caldesmon Antikörper wird verwendet zum Nachweis von Caldesmon in Proben von Human. Er wurde validiert für WB, IHC und ELISA.

Kurzübersicht für Caldesmon Antikörper (ABIN347045)

Target: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caldesmon Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Caldesmon Antikörper

Spezifität: Reacts with human L-Caldesmon

Aufreinigung: Antiserum

Immunogen: A 15 residue synthetic peptide derived from human L-Caldesmon

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC(1:50 - 1:500) WB(1:200- 1:5000)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu Caldesmon

Target: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Andere Bezeichnung: L-Caldesmon

Hintergrund: Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration

Gen-ID: 800

UniProt: Q05682

Pathways: Myometrial Relaxation and Contraction