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Caldesmon Antikörper (AA 1-120)

CALD1 Reaktivität: Human, Ratte, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN4886498
  • Target Alle Caldesmon (CALD1) Antikörper anzeigen
    Caldesmon (CALD1) (Caldesmon 1 (CALD1))
    Bindungsspezifität
    • 26
    • 15
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-120
    Reaktivität
    • 84
    • 81
    • 62
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 100
    • 19
    Kaninchen
    Klonalität
    • 83
    • 36
    Polyklonal
    Konjugat
    • 73
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Caldesmon Antikörper ist unkonjugiert
    Applikation
    • 72
    • 32
    • 31
    • 27
    • 26
    • 18
    • 17
    • 17
    • 11
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Caldesmon(CALD1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Caldesmon(CALD1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: caldesmon 1
    Protein Name: Caldesmon
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E. coli-derived human Caldesmon recombinant protein (Position: M1-E120). Human Caldesmon shares 87.6% amino acid (aa) sequence identity with rat Caldesmon.
    Isotyp
    IgG
    Top Product
    Discover our top product CALD1 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    Caldesmon (CALD1) (Caldesmon 1 (CALD1))
    Andere Bezeichnung
    CALD1 (CALD1 Produkte)
    Synonyme
    CDM antikoerper, H-CAD antikoerper, HCAD antikoerper, L-CAD antikoerper, LCAD antikoerper, NAG22 antikoerper, l-Cad antikoerper, 4833423D12Rik antikoerper, AI195384 antikoerper, AV071549 antikoerper, AW536160 antikoerper, C920027I18Rik antikoerper, CALD1 antikoerper, Caldesmon antikoerper, caldesmon 1 antikoerper, CALD1 antikoerper, Cald1 antikoerper
    Hintergrund
    Caldesmon is a protein that in humans is encoded by the CALD1 gene. It is mapped to 7q33. This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

    Synonyms: CAD | CALD 1 | CALD1 | CALD-1 | Caldesmon 1 | Caldesmon1 | Caldesmon-1 | Caldesmon | CDM | HCAD | H CAD | H-CAD | LCAD | L CAD | L-CAD | NAG22 | Q05682
    Gen-ID
    800
    UniProt
    Q05682
    Pathways
    Myometrial Relaxation and Contraction
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