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Rekombinanter Caldesmon Antikörper

CALD1 Reaktivität: Human, Ratte IHC, StM Wirt: Kaninchen Monoclonal CALD1-1424R unconjugated Recombinant Antibody
Produktnummer ABIN6940942
  • Target Alle Caldesmon (CALD1) Antikörper anzeigen
    Caldesmon (CALD1) (Caldesmon 1 (CALD1))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 84
    • 81
    • 63
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 100
    • 19
    Kaninchen
    Klonalität
    • 84
    • 35
    Monoklonal
    Konjugat
    • 73
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Caldesmon Antikörper ist unkonjugiert
    Applikation
    • 73
    • 31
    • 31
    • 27
    • 26
    • 19
    • 17
    • 17
    • 11
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Spezifität
    Recognizes a protein of 150 kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120'150 kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70'80 kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150 kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant human full-length CALD1 protein
    Klon
    CALD1-1424R
    Isotyp
    IgG
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  • Applikationshinweise

    Positive Control: Uterus, Blood vessels in all tissues, smooth muscle or leiomyosarcoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA, pH 7.5-8.5, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    Caldesmon (CALD1) (Caldesmon 1 (CALD1))
    Andere Bezeichnung
    CALD1 (CALD1 Produkte)
    Synonyme
    CDM antikoerper, H-CAD antikoerper, HCAD antikoerper, L-CAD antikoerper, LCAD antikoerper, NAG22 antikoerper, l-Cad antikoerper, 4833423D12Rik antikoerper, AI195384 antikoerper, AV071549 antikoerper, AW536160 antikoerper, C920027I18Rik antikoerper, CALD1 antikoerper, Caldesmon antikoerper, caldesmon 1 antikoerper, CALD1 antikoerper, Cald1 antikoerper
    Molekulargewicht
    150kDa
    Gen-ID
    800
    UniProt
    Q05682
    Pathways
    Myometrial Relaxation and Contraction
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