Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GFAP in IHC und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Rind (Kuh), Schwein, Meerschweinchen, Schaf und Ziege.
IHC, ICC (frozen or formalin–fixed paraffin-embedded (FFPE) tissue sections, cell smears) 1:50-1:200 using streptavidin-Biotin system or polymer system. Prediluted antibody is used directly without dilution. The optimum dilution should be determined by the individual lab. Positive Control: Human brain or astrocytoma. Cellular Localization: Cytoplasmic.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
The antibody is supplied with 1% BSA in PBS with 0.05% azide, pH 7.4. The Prediluted antibody is supplied in our Universal antibody dilution buffer (AR-6526) green in color.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Target
GFAP
(Glial Fibrillary Acidic Protein (GFAP))
Andere Bezeichnung
GFAP
Hintergrund
Gilial Fibrillary acidic protein (GFAP), a 51 kDa an intermediate filament protein is closely related to non-epithelial family members, Vimentin, desmin and peripherin, which are all involved in structure and function of cell cytoskeleton. GFAP is expressed in central nervous system (CNS) in the astrocytes cells, functioning in cellular processes e.g. cell structure, movements, cell communication, brain processes and brain functions. This antibody stains astrocytes, glial cells, ependymal cells and their corresponding tumors. In the peripheral nervous system , it stains Schwann cells, satellite and enteric glial cells. This antibody distinguishes neoplasm of astrocytes origin from other neoplasm of CNS.