TLR1 Antikörper (N-Term)

Produktnummer ABIN318756

Der Kaninchen Polyklonal anti-TLR1 Antikörper (ABIN318756) detektiert spezifisch TLR1 in WB und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für TLR1 Antikörper (N-Term) (ABIN318756)

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-TLR1 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Affinity Chromatography

Immunogen: A 16 amino acid peptide located near the amino terminus of Human CD281

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on frozen sections: 10g/mL. Western Blot: 1 - 4g/mL, detects a band of approximately 90 kDa in mouse spleen lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu TLR1

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Andere Bezeichnung: CD281 / TLR1

Hintergrund: TLRs recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, and serve as an important link between the innate and adaptive immune response through the production of cytokines. TLR1 is co-expressed with TLR2 on monocytes and dendritic cells where they form heterodimers that can recognize peptidoglycan and bacterial lipopeptides, and in particular triacylated lipoproteins. TLR1 can also regulate other TLR responses, TLR1 can associate with TLR4 and inhibit its signalling in endothelial cells, and can associate with TLR2 to inhibit the TLR2/TLR6 mediated response to phenol-soluble modulin.Synonyms: KIAA0012, TIL, Toll-like receptor 1, Toll/interleukin-1 receptor-like protein

Gen-ID: 9606

UniProt: Q15399

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades