VIPR1 Antikörper

Produktnummer ABIN317871

Produktdetails anti-VIPR1 Antikörper

Target: VIPR1 (Vasoactive Intestinal Peptide Receptor 1 (VIPR1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VIPR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of VPAC1 protein. (region surrounding Val371)

Aufreinigung: Affinity chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: PBS, pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu VIPR1

Target: VIPR1 (Vasoactive Intestinal Peptide Receptor 1 (VIPR1))

Abstract: VIPR1 Produkte

Synonyme: HVR1 antikoerper, II antikoerper, PACAP-R-2 antikoerper, PACAP-R2 antikoerper, RDC1 antikoerper, V1RG antikoerper, VAPC1 antikoerper, VIP-R-1 antikoerper, VIPR antikoerper, VIRG antikoerper, VPAC1 antikoerper, VPAC1R antikoerper, VPCAP1R antikoerper, CVIPR antikoerper, AV071699 antikoerper, VIP-R1 antikoerper, RATVASREC antikoerper, VASREC antikoerper, VIPR1 antikoerper, LOC100226500 antikoerper, vipr1 antikoerper, hvr1 antikoerper, rdc1 antikoerper, v1rg antikoerper, vipr antikoerper, virg antikoerper, vapc1 antikoerper, vpac1 antikoerper, vpcap1 antikoerper, vpac1-r antikoerper, VIP-R antikoerper, vasoactive intestinal peptide receptor 1 antikoerper, vasoactive intestinal peptide receptor 1b antikoerper, vasoactive intestinal peptide receptor 1 S homeolog antikoerper, vasoactive intestinal polypeptide receptor antikoerper, VIPR1 antikoerper, Vipr1 antikoerper, vipr1b antikoerper, vipr1 antikoerper, vipr1.S antikoerper, LOC100303683 antikoerper

Hintergrund: The vasoactive intestinal peptide (VIP) and the pituitary adenylate cylaseactivating polypeptide (PACAP) belong to a superfamily of peptide hormones that include glucagon, secretin and growth hormone releasing hormone. The effects of VIP and PACAP are mediated by three G-protein coupled receptors, VPAC1, VPAC2 and the PACAP receptor (also designated PAC1-R). The VPAC receptors have equal affinities for VIP and PACAP, which stimulate the activation of adenylyl cyclase. Both VPAC1, a 47 kDa protein, and VPAC2, a 65 kDa protein, are abundantly expressed in brain and T cells, where they modulate neuronal differentiation and T cell activation, respectively. The PACAP receptor is a seven transmembrane protein that produces at least eight isoforms by alternative splicing. Each isoform is associated with a specific signaling pathway and a specific expression pattern. The PACAP receptor, which is thought to play an integral role in brain development, preferentially binds PACAP in order to stimulate a cAMP-protein kinase A signaling pathway.Synonyms: PACAP-R-2, PACAPR2, Pituitary adenylate cyclase-activating polypeptide type II receptor, VIP-R1, VIPR-1, VIPR1, Vasoactive intestinal polypeptide receptor 1

Molekulargewicht: approx. 52 kDa

Gen-ID: 7433

NCBI Accession: NP_004615

UniProt: P32241