Adenosine A2a Receptor Antikörper

Produktnummer ABIN317694

Produktdetails anti-Adenosine A2a Receptor Antikörper

Target: Adenosine A2a Receptor (ADORA2A)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adenosine A2a Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects endogenous levels of Adenosine A2A-R protein.(region surrounding Tyr361)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1000approx. 1/10000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Adenosine A2a Receptor

Target: Adenosine A2a Receptor (ADORA2A)

Andere Bezeichnung: Adenosine Receptor A2a (ADORA2A Produkte)

Synonyme: ADORA2A antikoerper, adora2a.1 antikoerper, zgc:194773 antikoerper, A2aR antikoerper, ADORA2 antikoerper, RDC8 antikoerper, A2AAR antikoerper, AA2AR antikoerper, A2ar antikoerper, ADENO antikoerper, Adora2l1 antikoerper, adora2a.2 antikoerper, zgc:193802 antikoerper, zgc:193822 antikoerper, adenosine A2a receptor antikoerper, adenosine A2a receptor a antikoerper, adenosine A2a receptor L homeolog antikoerper, adenosine A2a receptor b antikoerper, ADORA2A antikoerper, Adora2a antikoerper, adora2aa antikoerper, adora2a.L antikoerper, adora2a antikoerper, adora2ab antikoerper

Hintergrund: Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response and the inhibition of protein synthesis. The adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthasis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFα and blocks the endotoxin CD14 receptor signal transduction pathway.Synonyms: ADORA2, ADORA2A

Molekulargewicht: approx. 45 kDa

Gen-ID: 135

NCBI Accession: NP_000666

UniProt: P29274

Pathways: Neurotrophin Signalübertragung, cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour, Cancer Immune Checkpoints