Annexin V Antikörper (Biotin)

Produktnummer ABIN317102

Produktdetails anti-Annexin V Antikörper (Biotin)

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Annexin V Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Spezifität: This antibody specifically recognises Annexin V. Clone VAA-33 has been reported to work in western blotting applications.

Produktmerkmale: Synonyms: Annexin-5, Annexin V, Lipocortin V, Endonexin II, Calphobindin I, Anchorin CII, ANX5, ENX2,PP4, CBP-I, PAP-I, VAC-alpha, Placental anticoagulant protein I, Placental anticoagulantprotein 4, Thromboplastin inhibitor, Vascular anticoagulant-alpha

Aufreinigung: Purified IgG prepared by affinity chromatography on Protein G

Immunogen: Recombinant Annexin V

Klon: VAA-33

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,2 mg/mL

Buffer: 50 mM Tris, 100 mM Nacl pH 7.4 containing 0.02 % Sodium Azide (NaN3), 1 % Bovine Serum Albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Annexin V

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Andere Bezeichnung: Annexin A5 / ANXA5 (ANXA5 Produkte)

Hintergrund: AnnexinV is a phospholipid binding protein which binds with high affinity and selectivity to phosphatidylserine (PS), in the presence of calcium. The translocation of PS from the cytosolic leaflet to the outer leaflet of the plasma membrane, due to a loss in plasma membrane asymmetry during apoptosis, acts as an in vivo signal for the removal of the dying cell by phagocytosis. Detection of PS using Annexin V therefore provides a reliable diagnostic tool for the indication of early programmed cell death. Annexin V has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Annexin V, are associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc).Synonyms: ANX5, Anchorin CII, Annexin V, Annexin-5, CBP-I, Calphobindin I, ENX2, Endonexin II, Lipocortin V, PAP-I, PP4, Placental anticoagulant protein 4, Placental anticoagulant protein I, Thromboplastin inhibitor, VAC-alpha, Vascular anticoagulant-alpha

Gen-ID: 308

UniProt: P08758

Pathways: Apoptose