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PD-1 Antikörper

PDCD1 Reaktivität: Maus FACS Wirt: Ratte Monoclonal RMP1-30 unconjugated
Produktnummer ABIN316894
  • Target Alle PD-1 (PDCD1) Antikörper anzeigen
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    Reaktivität
    • 160
    • 92
    • 26
    • 5
    • 3
    • 1
    Maus
    Wirt
    • 85
    • 80
    • 42
    • 13
    • 4
    • 2
    • 2
    • 2
    • 1
    Ratte
    Klonalität
    • 165
    • 60
    • 5
    Monoklonal
    Konjugat
    • 116
    • 16
    • 13
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PD-1 Antikörper ist unkonjugiert
    Applikation
    • 144
    • 68
    • 52
    • 51
    • 39
    • 20
    • 13
    • 13
    • 13
    • 11
    • 11
    • 11
    • 10
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    This antibody recognises CD279, a 55 kDa cell surface protein which is a member of the CD28/CTLA-4 family, otherwise known as Programmed Death-1 (PD-1). Antibodies produced by clone RMP1-30 do not block the binding of both B7-H1-Ig and B7-DC-Ig fusion proteins to PD-1 transfected BHK cells.
    Produktmerkmale
    Synonyms: Protein PD-1, hPD-1, PDCD1, Programmed cell death protein 1
    Aufreinigung
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    Immunogen
    PD-1 transferred BHK cells
    Klon
    RMP1-30
    Isotyp
    IgG2b
    Top Product
    Discover our top product PDCD1 Primärantikörper
  • Applikationshinweise
    Flow Cytometry: 1/100 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4, 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.
    Haltbarkeit
    12 months
  • Target
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    Andere Bezeichnung
    CD279 / PD1 (PDCD1 Produkte)
    Hintergrund
    CD279 is expressed predominantly on activated T- and B- lymphocytes and on a subset of thymocytes. Studies suggest that CD279, an immunoinhibitory receptor, plays a critical role in peripheral tolerance induction and prevention of autoimmune disease. Two members of the B7 family, B7-H1 (PD-L1) and B7-DC (PD-L2), have been identified as the ligands for CD279.Synonyms: PDCD1, Programmed cell death protein 1, Protein PD-1, hPD-1
    Gen-ID
    18566
    UniProt
    Q02242
    Pathways
    Cancer Immune Checkpoints
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