Optimal working dilutions should be determined experimentally by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Lagerung
-20 °C
Target
GFRA3
(GDNF Family Receptor alpha 3 (GFRA3))
Hintergrund
GDNF, Neurturin, Artemin, and Persephin are distant members of the TGF-beta superfamily that function as neurotrophic factors. Their bioactivities are mediated by a receptor complex composed of the non-ligand-binding signaling subunit (c-Ret receptor tyrosine kinase) and one of four ligand binding subunits designated GFR alpha-1 through 4, which are cysteine-rich glycosyl-phosphatidylinositol (GPI)-linked cell surface proteins. Note: For IHC, we recommendFormalin-Fixed Paraffin-Embedded (FFPE) tissue only.