SMO Antikörper
Kurzübersicht für SMO Antikörper (ABIN307155)
Target
Alle SMO Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Rabbit anti Human SMO (Smoothened Homolog)
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Kreuzreaktivität
- Human
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Produktmerkmale
- SMO is a G protein-coupled receptor (GPCR) that putatively associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. The binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). In basal cell carcinoma there are two somatic mutations SMO, D473-> H473 and R562 ->Q562.
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Aufreinigung
- Ammonium Sulfate Precipitation
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Immunogen
- Synthetic peptide derived from the human SMO protein
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Isotyp
- IgG
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Applikationshinweise
- Antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- SMO (Smoothened Homolog (Drosophila) (SMO))
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Andere Bezeichnung
- SMO (Smoothened Homolog)
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Hintergrund
- Smoothened homolog [Precursor], SMO, Gx protein, SMO, SMOH
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UniProt
- Q99835
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Pathways
- Hedgehog Signalweg
Target
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