CAPNL1 Antikörper

Produktnummer ABIN306693

Der Maus Monoklonal anti-CAPNL1 Antikörper (Klon 15C10) (ABIN306693) detektiert spezifisch CAPNL1 in WB, IP und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Rind (Kuh).

Kurzübersicht für CAPNL1 Antikörper (ABIN306693)

Target: CAPNL1 (Calpain 1, Large Subunit (CAPNL1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CAPNL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Klon: 15C10

Produktdetails anti-CAPNL1 Antikörper

Verwendungszweck: Mouse anti Human Calpain I (large subunit, p80)

Kreuzreaktivität: Rind (Kuh), Human, Maus, Ratte

Produktmerkmale: The calpains are calcium-dependent cysteine proteases that are widely expressed in mammalian systems. Both m-calpain (calpain II) and μ-calpain (calpain I) are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kD subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca ++ requirements that are suggested by their names. Whereas m-calpain requires millimolar ( mM) levels of calcium, μ-calpain is active at micromolar (uM) concentrations of Ca ++. In addition to the ubiquitously expressed m- and μcalpains, some tissue-specific calpains have been identified. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.

Aufreinigung: Protein A/G Chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Use at 0.5-1 μg/mL for ELISA and Western blot, 1-2 μg/mL for immunoprecipitation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu CAPNL1

Target: CAPNL1 (Calpain 1, Large Subunit (CAPNL1))

Hintergrund: Mouse Anti-Calpain I, u-Calpain (Large subunit, p80), Monoclonal Antibody

UniProt: P07384

Pathways: Apoptose