PPP2R5D Antikörper

Produktnummer ABIN306653

Der Kaninchen Polyklonal anti-PPP2R5D Antikörper wird verwendet zum Nachweis von PPP2R5D in Proben von Human, Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für PPP2R5D Antikörper (ABIN306653)

Target: PPP2R5D (Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2R5D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PPP2R5D Antikörper

Verwendungszweck: Rabbit anti Human Protein Phosphatase 2 A/B delta

Kreuzreaktivität: Rind (Kuh), Human, Maus, Ratte

Produktmerkmale: PP2A is a heterotrimeric phosphatase, ccomposed of A, B and C subunits. The structural A and catalytic C subunits form the constitutive core of the enzyme, which associates with one of a large number of regulatory B subunits. Three families of B subunits have been identified thus far. The prototypical B (or PR55) family of subunits is encoded by three genes, B , B and B . The B' (or B56) family consists of at least seven splice variants derived from five genes. RNA's for the two members of the B'' family, PR72 and PR130, arise by alternative splicing or use of alternate transcription start sites from the same gene. Primary structures as well as functions of B and B' subunits are conserved from yeast to mammals. B is a novel isoform of the B class of PP2A regulatory subunits. It is widely expressed in rat tissues and appears to be involved in targeting PP2A to the cytosolic compartment.

Aufreinigung: Ammonium Sulfate Precipitation

Immunogen: Synthetic peptide conjugated to KLH derived from the N-terminus of PP2A/B delta

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Detects PP2A/B delta protein in rat testis by Western blot. Detects a 53 kDa band in rat brain, heart, lung, placenta, skeletal muscle, spleen, testis and thymus tissues lysates. Optimal concentration should be evaluated by serial dilutions. Applications: Western Blotting, Immunofluorescence

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu PPP2R5D

Target: PPP2R5D (Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D))

Andere Bezeichnung: Protein Phosphatase 2 A/B delta

Hintergrund: Pp2A/Bd, rabbit anti protein phosphatase 2A, B subunit delta, PP2A B subunit delta

UniProt: Q14738, Q925E7, P56932

Pathways: PI3K-Akt Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades