Retinoblastoma Protein (Rb) Antikörper
-
- Target Alle Retinoblastoma Protein (Rb) (Rb Protein) Antikörper anzeigen
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
-
Reaktivität
- Human, Maus, Ratte, Huhn
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser Retinoblastoma Protein (Rb) Antikörper ist unkonjugiert
- Applikation
- Bitte anfragen
- Klon
- XZ133
- Isotyp
- IgG1
- Top Product
- Discover our top product Rb Protein Primärantikörper
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
- Target
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
- Andere Bezeichnung
- Rb (Retinoblastoma) (Rb Protein Produkte)
- Hintergrund
- The immunogen for the anti-human retinoblastoma (Rb) was a recombinant protein corresponding to amino acids 393 to 572 of the human retinoblastoma sequence. Retinoblastoma encodes a phosphorylated protein p110 and binds and regulates E2F transcription factors. Rb functions as a major cell cycle regulator by its ability to repress gene transcription by all three RNA polymerases. In its hypophosphorylated form, Rb binds to a subset of E2F containing complexes converting them to repressors preventing expression of E2F target genes. These complexes repress transcription via E2F binding elements in the promotersof cell cycle control genes, such as E2F-1, c-myc, and cdc2 genes. Synonyms: Retinoblastoma-associated protein, pRb, pp110, p105-Rb.
- UniProt
- P06400
- Pathways
- Mitotic G1-G1/S Phases
-