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Retinoblastoma Protein (Rb) Antikörper

Rb Protein Reaktivität: Human, Maus, Ratte, Huhn Wirt: Maus Monoclonal XZ133 unconjugated
Produktnummer ABIN306635
  • Target Alle Retinoblastoma Protein (Rb) (Rb Protein) Antikörper anzeigen
    Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
    Reaktivität
    • 131
    • 38
    • 25
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Huhn
    Wirt
    • 108
    • 24
    Maus
    Klonalität
    • 106
    • 26
    Monoklonal
    Konjugat
    • 70
    • 13
    • 10
    • 9
    • 9
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Retinoblastoma Protein (Rb) Antikörper ist unkonjugiert
    Applikation
    Bitte anfragen
    Klon
    XZ133
    Isotyp
    IgG1
    Top Product
    Discover our top product Rb Protein Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Target
    Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
    Andere Bezeichnung
    Rb (Retinoblastoma) (Rb Protein Produkte)
    Hintergrund
    The immunogen for the anti-human retinoblastoma (Rb) was a recombinant protein corresponding to amino acids 393 to 572 of the human retinoblastoma sequence. Retinoblastoma encodes a phosphorylated protein p110 and binds and regulates E2F transcription factors. Rb functions as a major cell cycle regulator by its ability to repress gene transcription by all three RNA polymerases. In its hypophosphorylated form, Rb binds to a subset of E2F containing complexes converting them to repressors preventing expression of E2F target genes. These complexes repress transcription via E2F binding elements in the promotersof cell cycle control genes, such as E2F-1, c-myc, and cdc2 genes. Synonyms: Retinoblastoma-associated protein, pRb, pp110, p105-Rb.
    UniProt
    P06400
    Pathways
    Mitotic G1-G1/S Phases
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