CD44 Antikörper (AA 21-145)

Produktnummer ABIN306452

Der Maus Monoklonal Anti-CD44-Antikörper wurde für FACS, WB, ELISA, IF und ICC validiert. Er ist geeignet, CD44 in Proben von Human zu detektieren.

Kurzübersicht für CD44 Antikörper (AA 21-145) (ABIN306452)

Target: CD44

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD44 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: 5C10

Produktdetails anti-CD44 Antikörper

Bindungsspezifität: AA 21-145

Aufreinigung: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Immunogen: Recombinant human CD44 (21-145aa) purified from E. coli

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Recommended dilution 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu CD44

Target: CD44

Andere Bezeichnung: CD44

Hintergrund: CD44 is a broadly distributed transmembrane glycoprotein that plays a critical role in a variety of cellular behaviors, including adhesion, migration, invasion, and survival. CD44 mediates cell-cell and cell-matrix interactions in a large part through its affinity for hyaluronan (HA), a glycosaminoglycan constituent of extracellular matrices, but also potentially through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Variants of CD44 are expressed in tissues during development, including embryonic epithelia. known functions of CD44 are cellular adhesion (aggregation and migration), hyaluronate degradation, lymphocyte activation, lymph node homing, myelopoiesis and lymphopoiesis, angiogenesis, and release of cytokines. The functions of CD44 are principally dependant on cellular adhesion in one setting or another.

NCBI Accession: NP_001001390

Pathways: Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling