PD-1 Antikörper (AA 21-167)

Produktnummer ABIN306438

Dieses Anti-PD-1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von PD-1 in FACS, WB, ELISA, IF und ICC. Geeignet für Human.

Kurzübersicht für PD-1 Antikörper (AA 21-167) (ABIN306438)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PD-1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: 4F12

Produktdetails anti-PD-1 Antikörper

Bindungsspezifität: AA 21-167

Aufreinigung: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Immunogen: Recombinant human PDCD1 (21-167aa) purified from E. coli

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Recommended dilution 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Andere Bezeichnung: PD-1

Hintergrund: PD-1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily, also known as Programmed Cell Death 1. It is expressed on activated T cell, B cells, myeloid cells and a subset of thymocytes. PD-1 interacts with expressed PDL1 and PDL2 to inhibit the proliferation and activation of T cells and B cells. Both PDL1 and PDL2 are expressed in a wide variety of normal tissues including heart, lung, placenta, spleen and kidney. PD-1 might be involved in the regulation of peripheral tolerance and may help prevent autoimmune diseases.

Pathways: Cancer Immune Checkpoints